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The Role of Postoperative Neurocognitive Dysfunction on Quality of Life for Postmenopausal Women 6 Months After Cardiac Surgery
Author(s) -
Charles W. Hogue,
Robert Fucetola,
Tamara Hershey,
Abullah Nassief,
Stanley J. Birge,
Víctor G. DávilaRomán,
Benico Barzilai,
Betsy Thomas,
Kenneth B. Schechtman,
Kenneth E. Freedland
Publication year - 2008
Publication title -
anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3181606a65
Subject(s) - medicine , neurocognitive , perioperative , quality of life (healthcare) , placebo , rating scale , cardiac surgery , surgery , anesthesia , cognition , psychiatry , nursing , alternative medicine , pathology , psychology , developmental psychology
Women are prone to neurological complications after cardiac surgery. We have previously reported that treatment perioperatively with the neuroprotectant steroid 17beta-estradiol did not improve neurocognitive end-points 4 to 6 wk after surgery for elderly women. In this study, we evaluated the influence of early postoperative neurocognitive dysfunction on quality of life in postmenopausal women undergoing cardiac surgery and whether it is impacted by perioperative 17beta-estradiol treatment.

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