Open AccessHydroxyethyl Starch and Acute Kidney Injury in Orthotopic Liver Transplantation
Author(s) -
William R. Hand,
Joseph Whiteley,
Tom I Epperson,
Lauren Tam,
Heather Crego,
Bethany J. Wolf,
Kenneth D. Chavin,
David J. Taber
Publication year - 2015
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000000374
Subject(s) - medicine , hydroxyethyl starch , acute kidney injury , rifle , liver transplantation , perioperative , albumin , intravascular volume status , creatinine , odds ratio , surgery , transplantation , anesthesia , hemodynamics , archaeology , history
Acute kidney injury (AKI) is a frequent complication of orthotopic liver transplantation (OLT). Hepatic failure pathophysiology and intraoperative events contribute to AKI after OLT. Colloids are routinely used to maintain intravascular volume during OLT. Recent evidence has implicated 6% hydroxyethyl starch (HES) (130/0.4) with AKI in critically ill patients.