Multiple sclerosis treatment: Some safety issues to keep in mind

Interferon drugs and the treatment of multiple sclerosis The treatment of multiple sclerosis (MS) has been revolutionized by the discovery of interferons. The interferons are man-made molecules that mimic the action of interferon molecules that are made by the body. The interferons are part of the immune system, which works to clear invaders from the body. The name “interferon” comes from “interference,” because they interfere with the growth of viruses. More information about MS can be found on the next page.In MS, part of the immune system reacts against myelin. Myelin is a cover that surrounds the nerves in the brain and allows them to carry impulses through the brain more efficiently. We believe treatment with interferons decreases the number of attacks on myelin. How are interferon drugs made? The interferon drugs are produced by bacteria ( Escherichia coli ) in the laboratory. All the interferon drugs have been shown to cause liver damage in some people. We detect this damage by measuring liver function tests in the blood. The interferon drugs are not only used for the treatment of MS. These medications have been used also for the treatment of hepatitis, myeloma, leukemia, and other diseases. How many inferferon drugs are there? There are three interferon drugs available for the treatment of MS: interferon B1a (Avonex), interferon B1b (Betaseron), and interferon B1a (Rebif). All of the interferon drugs must be injected. None are available to take by mouth. The interferon drugs have different doses and routes of injection. Betaseron is injected every other day subcutaneously (under the skin). Rebif is injected three times per …