Open AccessInvestigation of antihypertensive class, dementia, and cognitive decline
Author(s) -
Ruth Peters,
Sevil Yaşar,
Craig S. Anderson,
Shea J. Andrews,
Riitta Antikaínen,
Hisatomi Arima,
Nigel Beckett,
Jacob Beer,
Anne Suzanne Bertens,
Andrew Booth,
Martin P.J. van Boxtel,
Carol Brayne,
Henry Brodaty,
Michelle C. Carlson,
John Chalmers,
María M. Corrada,
Steven T. DeKosky,
Carol A. Derby,
Roger A. Dixon,
Françoise Forette,
Mary Ganguli,
Willem A. van Gool,
Antonio Guaita,
Ann Hever,
David B. Hogan,
Carol Jagger,
Mindy J. Katz,
Claudia H. Kawas,
Patrick Gavin Kehoe,
Sirkka KeinänenKiukaanniemi,
Rose Anne Kenny,
Sebastian Köhler,
Setor K Kunutsor,
Jari A. Laukkanen,
Colleen J. Maxwell,
G. Peggy McFall,
Tessa van Middelaar,
Eric P. Moll van Charante,
Tze Pin Ng,
Jean Peters,
Iris Rawtaer,
Edo Richard,
Kenneth Rockwood,
Lina Rydén,
Perminder S. Sachdev,
Ingmar Skoog,
Johan Skoog,
Jan A. Staessen,
Blossom Christa Maree Stephan,
Sylvain Sebért,
Lutgarde Thijs,
Stella Trompet,
Phillip J. Tully,
Christophe Tzourio,
Roberta Vaccaro,
Eeva Vaaramo,
Erin Walsh,
Jane Warwick,
Kaarin J. Anstey
Publication year - 2020
Publication title -
neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.91
H-Index - 364
eISSN - 1526-632X
pISSN - 0028-3878
DOI - 10.1212/wnl.0000000000008732
Subject(s) - dementia , medicine , psycinfo , cognitive decline , meta analysis , cognition , clinical trial , medline , blood pressure , randomized controlled trial , physical therapy , psychiatry , disease , political science , law
High blood pressure is one of the main modifiable risk factors for dementia. However, there is conflicting evidence regarding the best antihypertensive class for optimizing cognition. Our objective was to determine whether any particular antihypertensive class was associated with a reduced risk of cognitive decline or dementia using comprehensive meta-analysis including reanalysis of original participant data.