Open AccessNew strategies for polymer development in pharmaceutical science — a short review
Author(s) -
Godwin A.,
Bolina K.,
Clochard M.,
Dinand E.,
Rankin S.,
Simic S.,
Brocchini S.
Publication year - 2001
Publication title -
journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 118
eISSN - 2042-7158
pISSN - 0022-3573
DOI - 10.1211/0022357011776612
Subject(s) - polymer , excipient , natural polymers , nanotechnology , materials science , biochemical engineering , polymer science , combinatorial chemistry , chemistry , organic chemistry , chromatography , engineering
We are developing synthetic polymers for pharmaceutical and medical applications. These applications can be broadly grouped on how the polymer will be utilized e.g. material, excipient or molecule. Our focus is to develop polymers with more defined structures that are based on biological, physicochemical and/or materials criteria. Strategies are being developed to more efficiently optimize structure—property correlations during preclinical development. We describe two examples of our research on pharmaceutical polymer development: narrow molecular weight distribution (MWD) homopolymeric precursors which can be functionalized to give families of narrow MWD homo‐ and co‐polymers, and hydrolytically degradable polymers.