Mitochondrial Localization and Regulation of BRAFV600E in Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAFV600E
Author(s) -
Min Hee Lee,
Seong Eun Lee,
Dong Wook Kim,
Min Jeong Ryu,
Sung Jin Kim,
Sung Joong Kim,
Yong Kyoung Kim,
Ji Hoon Park,
Gi Ryang Kweon,
JinMan Kim,
Jung Uee Lee,
Valentina De Falco,
Young Suk Jo,
Minho Shong
Publication year - 2010
Publication title -
molecular endocrinology
Language(s) - English
Resource type - Journals
eISSN - 1944-9917
pISSN - 0888-8809
DOI - 10.1210/mend.24.11.9999
Subject(s) - biology , mapk/erk pathway , sorafenib , mitochondrion , kinase , staurosporine , cancer research , oxidative phosphorylation , thyroid cancer , apoptosis , cancer cell , phosphorylation , mitochondrial ros , glycolysis , cancer , microbiology and biotechnology , protein kinase a , biochemistry , metabolism , genetics , hepatocellular carcinoma
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom