Localization of Inhibin/Activin Subunit mRNAs within the Primate Ovary | Zendy

Ralph Schwall | Zendy; Anthony J. Mason | Zendy; J N Wilcox | Zendy; Steven G. Bassett | Zendy; Anthony J. Zeleznik | Zendy

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Localization of Inhibin/Activin Subunit mRNAs within the Primate Ovary

Author(s) -

Ralph Schwall,

Anthony J. Mason,

J N Wilcox,

Steven G. Bassett,

Anthony J. Zeleznik

Publication year - 1990

Publication title -

molecular endocrinology

Language(s) - English

Resource type - Journals

eISSN - 1944-9917

pISSN - 0888-8809

DOI - 10.1210/mend-4-1-75

Subject(s) - biology , ovary , in situ hybridization , antral follicle , messenger rna , protein subunit , endocrinology , medicine , alpha (finance) , beta (programming language) , ovarian follicle , gene , genetics , patient satisfaction , programming language , construct validity , nursing , computer science

In order to gain further understanding of the physiology of inhibin and activin in the primate, the expression of inhibin/activin subunit mRNAs in the monkey ovary was examined by in situ hybridization. Granulosa cells of small antral follicles were found to express mRNA for the beta B subunit, which decreased to undetectable levels in dominant follicles. In contrast, expression of alpha and beta A subunit mRNAs was detected in granulosa cells of dominant follicles and in corpora lutea, but not in small antral follicles. These results indicate that the expression of the beta A and beta B subunits is differentially regulated during the growth and development of ovarian follicles in the monkey.

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