Open AccessCommentary: The Year in Orphan Nuclear Receptors and Their Coregulators
Author(s) -
David D. Moore
Publication year - 2011
Publication title -
molecular endocrinology
Language(s) - English
Resource type - Journals
eISSN - 1944-9917
pISSN - 0888-8809
DOI - 10.1210/me.2011-1228
Subject(s) - biology , nuclear receptor , receptor , neuron derived orphan receptor 1 , computational biology , pathological , orphan receptor , genetics , bioinformatics , neuroscience , transcription factor , gene , medicine
We are beginning to integrate the functions of individual orphan receptors into larger networks. It is particularly exciting that these basic studies are beginning to shed light on important diseases. We are now able to address not just physiological but also pathological functions of these proteins and their potential as targets for treating a surprisingly wide range of diseases.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom