P450c17 Mutations R347H and R358Q Selectively Disrupt 17,20-Lyase Activity by Disrupting Interactions with P450 Oxidoreductase and Cytochrome b5
Author(s) -
David H. Geller
Publication year - 1999
Publication title -
molecular endocrinology
Language(s) - English
Resource type - Journals
eISSN - 1944-9917
pISSN - 0888-8809
DOI - 10.1210/me.13.1.167
Subject(s) - cytochrome b5 , mutant , biology , cytochrome p450 , pregnenolone , lyase , enzyme , biochemistry , oxidoreductase , cytochrome , microsome , yeast , microbiology and biotechnology , gene , steroid , hormone
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