A Case Series of Patients with Isolated IgG4-related Hypophysitis Treated with Rituximab
Author(s) -
Hessa Boharoon,
James Tomlinson,
Clara Limbӓck-Stanic,
Anastasia Gontsorova,
Niamh Martin,
Emma Hatfield,
Karim Meeran,
Ramesh Nair,
Nigel Mendoza,
Jeremy Levy,
Stephen P. McAdoo,
Charles D. Pusey,
Florian Wernig
Publication year - 2020
Publication title -
journal of the endocrine society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.046
H-Index - 20
ISSN - 2472-1972
DOI - 10.1210/jendso/bvaa048
Subject(s) - rituximab , medicine , hypophysitis , gastroenterology , igg4 related disease , surgery , disease , pituitary gland , hormone , lymphoma
Rituximab treatment for IgG4-related hypophysitis resulted in sustained remission in 2 patients treated early in the disease process but only achieved partial response in a patient with chronic disease, suggesting that early therapeutic intervention may be crucial in order to avoid irreversible changes.
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