SUN-613 Association of Electrocardiograph Parameters and Diabetic Peripheral Neuropathy

Aim: The purpose of this study was to assess the relation between Prolonged P wave duration with diabetic peripheral neuropathy in subjects with type 2 diabetes. Methods: We assessed the measures of electrocardiographic function in 105 in 147 Korean subjects with type 2 diabetes, who visited Dongguk University Hospital for regular health checkup using electrocardiogram (ECG). We measured several electrocardiogram parameters including ventricular rate, PR interval, QRS duration, QT, QTC and P wave duration. Subjects were grouped as without diabetic peripheral neuropathy (≤2) and with peripheral neuropathy (≥2) based on Michigan Neuropathy Screening Instrument Examination Score (MNSIES). Results: The population mean age was 61.50±11.17 years and 60.78% were men. The participants with DPN significantly found higher with age, MNSIES and P wave duration as compared to without DPN. The prevalence of drinking significantly found higher in participants with diabetic peripheral neuropathy. Furthermore, in a multiple regression analysis, MNSI examination score significantly showed positive association with prolonged P wave duration after adjustment with age, MNSIES and drinking alcohol(β, 1.123; 95% CI, .109∼2.138; p=.030). Conclusions: The current study revealed an association between prolonged P wave and MNSI examination score.