Open AccessObesity-Linked Variants of Melanocortin-4 Receptor Are Misfolded in the Endoplasmic Reticulum and Can Be Rescued to the Cell Surface by a Chemical Chaperone
Author(s) -
Susana Granell,
Sameer Mohammad,
Ramanagouda RamanagoudrBhojappa,
Giulia Baldini
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jcem.95.8.9990
Subject(s) - endoplasmic reticulum , chemical chaperone , microbiology and biotechnology , melanocortin , melanocortin 4 receptor , chaperone (clinical) , receptor , cell , obesity , chemistry , biology , endocrinology , unfolded protein response , biochemistry , medicine , pathology
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