Preserved Adrenocortical Function After Laparoscopic Bilateral Adrenal Sparing Surgery for Hereditary Pheochromocytoma1 | Zendy

Hartmut P.H. Neumann | Zendy; Martín Reincke | Zendy; Bernhard U. Bender | Zendy; Romy Elsner | Zendy; Günter Janetschek | Zendy

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Preserved Adrenocortical Function After Laparoscopic Bilateral Adrenal Sparing Surgery for Hereditary Pheochromocytoma¹

Author(s) -

Hartmut P.H. Neumann,

Martín Reincke,

Bernhard U. Bender,

Romy Elsner,

Günter Janetschek

Publication year - 1999

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jcem.84.8.5872

Subject(s) - medicine , pheochromocytoma , asymptomatic , aldosterone , endocrine disease , surgery , multiple endocrine neoplasia , vanillylmandelic acid , adrenocortical carcinoma , epinephrine , endocrine system , endocrinology , hormone , homovanillic acid , biochemistry , chemistry , receptor , serotonin , gene

Familial pheochromocytoma, increasingly diagnosed in asymptomatic subjects with inherited syndromes such as multiple endocrine neoplasia type 2 and Von Hippel-Lindau disease, is frequently bilateral and multifocal, but very rarely malignant. Therefore, bilateral adrenalectomy and subsequent lifelong steroid replacement, with its attendant side effects, is not desirable. Minimally invasive adrenal sparing surgery by means of laparoscopy was explored for the treatment of bilateral pheochromocytoma. We report on the cure rate and adrenocortical function in a series of patients treated accordingly.

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