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Cross Genotype Sex Hormone Treatment in Two Cases of Hypogonadal Osteoporosis
Author(s) -
Iris Vered,
Igor Kaiserman,
BenAmi Sela,
Joseph Sack
Publication year - 1997
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jcem.82.2.3695
Subject(s) - medicine , endocrinology , osteoporosis , bone mineral , testosterone (patch) , estrogen , sex hormone binding globulin , osteopenia , hormone , androgen
Sex hormone deficiency is the most common cause of bone loss. Reduced bone mass and an increased risk for osteoporotic fractures have been described in hypogonadal subjects of both sexes. We present here the results of treating two patients showing abnormal sexual differentiation (an XX male and an XY female), who suffered from bone loss related to sex hormone deficiency, with cross genotype sex hormones.

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