Exercise Induction of Key Transcriptional Regulators of Metabolic Adaptation in Muscle Is Preserved in Type 2 Diabetes | Zendy

Rugivan Sabaratnam | Zendy; Andreas James Thestrup Pedersen | Zendy; Tilde Eskildsen | Zendy; Jonas M. Kristensen | Zendy; Jørgen F. P. Wojtaszewski | Zendy; Kurt Højlund | Zendy

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Exercise Induction of Key Transcriptional Regulators of Metabolic Adaptation in Muscle Is Preserved in Type 2 Diabetes

Author(s) -

Rugivan Sabaratnam,

Andreas James Thestrup Pedersen,

Tilde Eskildsen,

Jonas M. Kristensen,

Jørgen F. P. Wojtaszewski,

Kurt Højlund

Publication year - 2019

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-02679

Subject(s) - adaptation (eye) , key (lock) , type 2 diabetes , biology , medicine , microbiology and biotechnology , endocrinology , diabetes mellitus , neuroscience , ecology

Type 2 diabetes (T2D) is characterized by insulin resistance in skeletal muscle. Regular exercise improves insulin sensitivity, mitochondrial function, and energy metabolism. Thus, an impaired response to exercise may contribute to insulin resistance.

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