Mifepristone Treatment in Four Cases of Primary Bilateral Macronodular Adrenal Hyperplasia (BMAH)
Author(s) -
Pejman Cohan,
Honey E. East,
Sandi-Jo Galati,
Jennifer U. Mercado,
Precious J Lim,
Michele Lamerson,
James J. Smith,
Anne L. Peters,
Kevin C.J. Yuen
Publication year - 2019
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-02638
Subject(s) - mifepristone , medicine , adrenalectomy , adverse effect , surgery , cushing syndrome , pregnancy , genetics , biology
Primary bilateral macronodular adrenal hyperplasia (BMAH) is a rare form of adrenal Cushing syndrome conventionally treated with adrenalectomy. Medical treatment is often reserved for patients not eligible for surgery. However, to date there have been few studies about the efficacy of mifepristone for the treatment of BMAH associated with hypercortisolism.
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