Open AccessFSHB −211 G>T Polymorphism as Predictor for TESE Success in Patients With Unexplained Azoospermia
Author(s) -
Alexander S. Busch,
Frank Tüttelmann,
JannFrederik Cremers,
Maria Schubert,
Vereordhoff,
Andreas N. Schüring,
Michael Zitzmann,
Jörg Gromoll,
Sabine Kliesch
Publication year - 2019
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-02249
Subject(s) - azoospermia , polymorphism (computer science) , medicine , genetics , biology , genotype , gene , pregnancy , infertility
Testicular sperm extraction (TESE) followed by assisted reproductive techniques often remains the only therapeutic option for men with azoospermia due to spermatogenic failure. Reproductive parameters, such as gonadotropin levels and testicular volume or histopathology, contribute to the prediction of sperm retrieval rate (SRR) in TESE. However, there is an eminent lack of noninvasive predictive factors for TESE outcome.
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