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Influence of Sodium Glucose Cotransporter 2 Inhibition on Physiological Adaptation to Endurance Exercise Training
Author(s) -
Alissa A. Newman,
Nathan C. Grimm,
Jessie R. Wilburn,
Hayden M. Schoenberg,
S. Raj J. Trikha,
Gary J. Luckasen,
Laurie M. Biela,
Christopher L. Melby,
Christopher Bell
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-01741
Subject(s) - endurance training , adaptation (eye) , cotransporter , training (meteorology) , sodium , endocrinology , medicine , chemistry , psychology , neuroscience , geography , meteorology , organic chemistry
The combination of two beneficial antidiabetes interventions, regular exercise and pharmaceuticals, is intuitively appealing. However, metformin, the most commonly prescribed diabetes medication, attenuates the favorable physiological adaptations to exercise; in turn, exercise may impede the action of metformin.

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