Lumbar Spine Bone Mineral Apparent Density in Children: Results from the Bone Mineral Density in Childhood Study | Zendy

Joseph M. Kindler | Zendy; Joan M. Lappe | Zendy; Vicente Gilsanz | Zendy; Sharon E. Oberfield | Zendy; John Shepherd | Zendy; Andrea Kelly | Zendy; Karen K. Winer | Zendy; Heidi J. Kalkwarf | Zendy; Babette S. Zemel | Zendy

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Lumbar Spine Bone Mineral Apparent Density in Children: Results from the Bone Mineral Density in Childhood Study

Author(s) -

Joseph M. Kindler,

Joan M. Lappe,

Vicente Gilsanz,

Sharon E. Oberfield,

John Shepherd,

Andrea Kelly,

Karen K. Winer,

Heidi J. Kalkwarf,

Babette S. Zemel

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-01693

Subject(s) - medicine , bone mineral , confounding , bone density , short stature , densitometry , population , lumbar spine , demography , osteoporosis , pediatrics , surgery , environmental health , sociology

Dual-energy X-ray absorptiometry (DXA) is a cornerstone of pediatric bone health assessment, yet differences in height-for-age confound the interpretation of areal bone mineral density (aBMD) measures. To reduce the confounding of short stature on spine bone density, use of bone mineral apparent density (BMAD) and height-for-age Z-score (HAZ)‒adjusted aBMD (aBMDHAZ) are recommended. However, spine BMAD reference data are sparse, and the degree to which BMAD and aBMDHAZ account for height-related artifacts in bone density remains unclear.

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