Comparison of Seated With Recumbent Saline Suppression Testing for the Diagnosis of Primary Aldosteronism | Zendy

Michael Stowasser | Zendy; Ashraf Ahmed | Zendy; Diane Cowley | Zendy; Martin Wolley | Zendy; Zeng Guo | Zendy; Brett McWhinney | Zendy; Jacobus Ungerer | Zendy; Richard D. Gordon | Zendy

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Comparison of Seated With Recumbent Saline Suppression Testing for the Diagnosis of Primary Aldosteronism

Author(s) -

Michael Stowasser,

Ashraf Ahmed,

Diane Cowley,

Martin Wolley,

Zeng Guo,

Brett McWhinney,

Jacobus Ungerer,

Richard D. Gordon

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-01394

Subject(s) - primary aldosteronism , medicine , aldosterone , saline , endocrinology , fludrocortisone , hydrocortisone

Failure of plasma aldosterone suppression during fludrocortisone suppression testing (FST) or saline suppression testing (SST) confirms primary aldosteronism (PA). Aldosterone is often higher upright than recumbent in PA; upright levels are used during FST. In a pilot study (24 patients with PA), seated saline suppression testing (SSST) was more sensitive than recumbent saline suppression testing (RSST).

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