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Sex Differences in the Prenatal Programming of Adult Metabolic Syndrome by Maternal Androgens
Author(s) -
Grace Huang,
Sara Cherkerzian,
Eric B. Loucks,
Stephen L. Buka,
Robert J. Handa,
Bill L. Lasley,
Shalender Bhasin,
Jill M. Goldstein
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-01243
Subject(s) - fetal programming , metabolic syndrome , medicine , pregnancy , physiology , obstetrics , biology , endocrinology , fetus , genetics , obesity
Growing preclinical evidence suggests that hormonal programming by androgens in utero may contribute to cardiovascular disease risk in adult offspring. However, the effect of prenatal androgens on cardiometabolic outcomes in the human population, especially their potential differential impact on male vs female offspring, has not been well studied.

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