Cardiometabolic Biomarkers and Their Temporal Patterns Predict Poor Outcome in Chronic Heart Failure (Bio-SHiFT Study)
Author(s) -
Miloš Branković,
K. Martijn Akkerhuis,
Henk Mouthaan,
Jasper J. Brugts,
Olivier C. Manintveld,
Jan van Ramshorst,
Tjeerd Germans,
Victor A. Umans,
Eric Boersma,
Isabella Kardys
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-01241
Subject(s) - medicine , heart failure , biomarker , resistin , hazard ratio , cardiology , heart type fatty acid binding protein , natriuretic peptide , framingham heart study , heart transplantation , adipokine , framingham risk score , leptin , disease , fatty acid binding protein , confidence interval , obesity , biochemistry , gene , chemistry
Multiple hormonal and metabolic alterations occur in chronic heart failure (CHF), but their proper monitoring during clinically silent progression of CHF remains challenging. Hence, our objective was to explore whether temporal patterns of six emerging cardiometabolic biomarkers predict future adverse clinical events in stable patients with CHF.
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