Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes
Author(s) -
Leen M. ‘t Hart,
Nicole Vogelzangs,
Dennis O. MookKanamori,
Adela Brahimaj,
Jano,
Amber A. van der Heijden,
Ko Willems van Dijk,
Roderick C. Slieker,
Ewout W. Steyerberg,
M. Arfan Ikram,
Marian Beekman,
Dorret I. Boomsma,
Cornelia M. van Duijn,
P. Eline Slagboom,
Coen D.A. Stehouwer,
Casper G. Schalkwijk,
Ilja C.W. Arts,
Joost Dekker,
Abbas Dehghan,
Taulant Muka,
Carla Kallen,
Giel Nijpels,
Marleen M. J. van Greevenbroek
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-01165
Subject(s) - glycemic , medicine , metabolomics , type 2 diabetes , insulin , diabetes mellitus , cohort , confounding , endocrinology , bioinformatics , biology
We studied whether blood metabolomic measures in people with type 2 diabetes (T2D) are associated with insufficient glycemic control and whether this association is influenced differentially by various diabetes drugs. We then tested whether the same metabolomic profiles were associated with the initiation of insulin therapy.
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