Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise
Author(s) -
Nikolaos Perakakis,
Vassilis Mougios,
Ioannis G. Fatouros,
Aikaterina Siopi,
Dimitrios Draganidis,
Natia Peradze,
Wael Ghaly,
Christos S. Mantzoros
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-01056
Subject(s) - follistatin , medicine , endocrinology , anthropometry , myostatin , vo2 max , body mass index , exercise physiology , metabolic syndrome , biology , obesity , heart rate , blood pressure , skeletal muscle
Clinical trials are evaluating the efficacy of inhibitors of the myostatin pathway in neuromuscular and metabolic diseases. Activins and follistatins are major regulators of the myostatin pathway, but their physiology in relation to metabolic and anthropometric variables and in response to exercise remains to be fully elucidated in humans.
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