Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue—Relation to Obesity and Weight Change | Zendy

Camilla A M Glad | Zendy; PerArne Svensson | Zendy; Fredrik H. Nyström | Zendy; Peter Jacobson | Zendy; Lena Carlsson | Zendy; Gudmundur Johannsson | Zendy; Johanna C. AnderssonAssarsson | Zendy

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Expression of GHR and Downstream Signaling Genes in Human Adipose Tissue—Relation to Obesity and Weight Change

Author(s) -

Camilla A M Glad,

PerArne Svensson,

Fredrik H. Nyström,

Peter Jacobson,

Lena Carlsson,

Gudmundur Johannsson,

Johanna C. AnderssonAssarsson

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-01036

Subject(s) - adipose tissue , human obesity , obesity , gene , downstream (manufacturing) , relation (database) , biology , microbiology and biotechnology , endocrinology , medicine , genetics , business , computer science , marketing , database

GH is a strong regulator of metabolism. In obesity, both GH secretion and adipose tissue GHR gene expression are decreased. More detailed information on the regulation of GHR, STAT3/5, and downstream-regulated genes in human adipose tissue during diet-induced weight loss and weight gain is lacking.

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