Role of wnt5a in Metabolic Inflammation in Humans | Zendy

I Relling | Zendy; Gül Akcay | Zendy; Daniela Fangmann | Zendy; Carina Knappe | Zendy; Dominik M. Schulte | Zendy; Katharina Hartmann | Zendy; Nike Müller | Zendy; Kathrin Türk | Zendy; Astrid Dempfle | Zendy; André Franke | Zendy; Stefan Schreiber | Zendy; Matthias Laudes | Zendy

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Role of wnt5a in Metabolic Inflammation in Humans

Author(s) -

I Relling,

Gül Akcay,

Daniela Fangmann,

Carina Knappe,

Dominik M. Schulte,

Katharina Hartmann,

Nike Müller,

Kathrin Türk,

Astrid Dempfle,

André Franke,

Stefan Schreiber,

Matthias Laudes

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-01007

Subject(s) - wnt5a , inflammation , biology , microbiome , endocrinology , medicine , nutrigenomics , wnt signaling pathway , physiology , immunology , genetics , gene

Common nutrition-associated diseases like obesity and type 2 diabetes are linked to chronic low-grade inflammation. The secreted glycopeptide wingless-type mouse mammary tumor virus integration site family member 5a (wnt5a) has been implicated in metabolic inflammation in rodent models, suggesting a potential treatment target. Data on the role of wnt5a in human physiology have yielded conflicting results.

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