Open AccessEvidence of a Causal Effect of Estradiol on Fracture Risk in Men
Author(s) -
Maria Nethander,
Liesbeth Vandenput,
Anna L. Eriksson,
Sara H. Windahl,
Thomas FunckBrentano,
Claes Ohlsson
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2018-00934
Subject(s) - mendelian randomization , medicine , observational study , bone mineral , body mass index , osteoporosis , endocrinology , physiology , genotype , biology , genetics , genetic variants , gene
Observational studies indicate that serum estradiol (E2) is more strongly associated with bone mineral density (BMD) than serum testosterone (T) is, whereas both E2 and T associate with fracture risk in men.
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