Oxandrolone Treatment Results in an Increased Risk of Gonadarche in Prepubertal Boys With Klinefelter Syndrome | Zendy

Shanlee Davis | Zendy; Najiba Lahlou | Zendy; Matthew Cox-Martin | Zendy; Karen Kowal | Zendy; Philip Zeitler | Zendy; Judith L. Ross | Zendy

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Oxandrolone Treatment Results in an Increased Risk of Gonadarche in Prepubertal Boys With Klinefelter Syndrome

Author(s) -

Shanlee Davis,

Najiba Lahlou,

Matthew Cox-Martin,

Karen Kowal,

Philip Zeitler,

Judith L. Ross

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-00682

Subject(s) - oxandrolone , medicine , testosterone (patch) , context (archaeology) , endocrinology , triptorelin , pubic hair , androgen , pediatrics , hormone , luteinizing hormone , gonadotropin releasing hormone , biology , growth hormone , paleontology

Klinefelter syndrome (KS) is a common genetic condition in which males have an extra X chromosome. KS is associated with testosterone deficiency, neurodevelopmental delays, and cardiometabolic disorders. There has been recent interest in prepubertal androgen treatment; however, the effects on puberty and gonadal function are unknown.

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