Microvascular Endothelial Dysfunction in Human Obesity: Role of TNF-α | Zendy

Agostino Virdis | Zendy; Rocchina Colucci | Zendy; Nunzia Bernardini | Zendy; Corrado Blandizzi | Zendy; Stefano Taddei | Zendy; Stefano Masi | Zendy

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Microvascular Endothelial Dysfunction in Human Obesity: Role of TNF-α

Author(s) -

Agostino Virdis,

Rocchina Colucci,

Nunzia Bernardini,

Corrado Blandizzi,

Stefano Taddei,

Stefano Masi

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-00512

Subject(s) - endothelial dysfunction , proinflammatory cytokine , adipose tissue , medicine , endocrinology , inflammation , vasodilation , endothelium , insulin resistance , microcirculation , obesity , nitric oxide , human obesity

Endothelium guarantees vascular homeostasis by the opposite action of substances by vasodilating/antithrombogenic and vasoconstricting/prothrombotic activities. Obesity is characterized by endothelial dysfunction associated with a condition of vascular low-grade inflammation.

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