Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD | Zendy

Eveline Bruinstroop | Zendy; Rinkoo Dalan | Zendy; Yang Cao | Zendy; Yong Mong Bee | Zendy; Kurumbian Chandran | Zendy; Li Wei Cho | Zendy; Shui Boon Soh | Zendy; Eng Kiong Teo | Zendy; SueAnne Toh | Zendy; Melvin KheeShing Leow | Zendy; Rohit A. Sinha | Zendy; Suresh Anand Sadananthan | Zendy; Navin Michael | Zendy; Heather M. Stapleton | Zendy; Christopher Leung | Zendy; Peter Angus | Zendy; Sheila K. Patel | Zendy; Louise M. Burrell | Zendy; Su Chi Lim | Zendy; Chee Fang Sum | Zendy; S. Sendhil Velan | Zendy; Paul M. Yen | Zendy

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Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD

Author(s) -

Eveline Bruinstroop,

Rinkoo Dalan,

Yang Cao,

Yong Mong Bee,

Kurumbian Chandran,

Li Wei Cho,

Shui Boon Soh,

Eng Kiong Teo,

SueAnne Toh,

Melvin KheeShing Leow,

Rohit A. Sinha,

Suresh Anand Sadananthan,

Navin Michael,

Heather M. Stapleton,

Christopher Leung,

Peter Angus,

Sheila K. Patel,

Louise M. Burrell,

Su Chi Lim,

Chee Fang Sum,

S. Sendhil Velan,

Paul M. Yen

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-00475

Subject(s) - levothyroxine , medicine , euthyroid , endocrinology , thyroid , nonalcoholic fatty liver disease , steatosis , fatty liver , diabetes mellitus , hormone , gastroenterology , type 2 diabetes mellitus , body mass index , disease

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with type 2 diabetes mellitus (T2DM) and associated with significant morbidity and mortality. Thyroid hormone (TH) increases β-oxidation of fatty acids and decreases intrahepatic lipid content (IHLC) in rodents with NAFLD.

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