Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose | Zendy

Henrik Maagensen | Zendy; Anders Junker | Zendy; Niklas Rye Jørgensen | Zendy; Lise Lotte Gluud | Zendy; Filip K. Knop | Zendy; Tina Vilsbøll | Zendy

Open Access

Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose

Author(s) -

Henrik Maagensen,

Anders Junker,

Niklas Rye Jørgensen,

Lise Lotte Gluud,

Filip K. Knop,

Tina Vilsbøll

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2018-00176

Subject(s) - nonalcoholic fatty liver disease , medicine , endocrinology , type 2 diabetes , diabetes mellitus , bone remodeling , carbohydrate metabolism , disease , fatty liver

Nonalcoholic fatty liver disease (NAFLD) is associated with type 2 diabetes (T2D) and vice versa, and both conditions are associated with an increased risk of fractures and altered bone turnover. Although patients with NAFLD typically suffer from decreased bone mineral density (BMD), T2D is associated with normal to high BMD. The pathophysiology is uncertain but may involve the gut-bone axis.

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