Pro-FHH: A Risk Equation to Facilitate the Diagnosis of Parathyroid-Related Hypercalcemia
Author(s) -
JeanPhilippe Bertocchio,
Muriel Tafflet,
Eugénie Koumakis,
Gérard Maruani,
Rosa VargasPoussou,
Caroline Silve,
Peter H. Nissen,
Stéphanie Baron,
Caroline ProtBertoye,
Marie Courbebaisse,
Jean–Claude Souberbielle,
Lars Rejnmark,
Catherine Cormier,
Pascal Houillier
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-02773
Subject(s) - medicine , primary hyperparathyroidism , parathyroidectomy , receiver operating characteristic , area under the curve , prospective cohort study , hyperparathyroidism , parathyroid hormone , context (archaeology) , urology , calcium , paleontology , biology
Parathyroid-related hypercalcemia is due to primary hyperparathyroidism (PHPT) or to familial hypocalciuric hypercalcemia (FHH). PHPT can lead to complications that necessitate parathyroidectomy. FHH is a rare genetic disease resembling PHPT; surgery is ineffective. A reliable method for distinguishing FHH from PHPT is needed.
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