GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability | Zendy

Long Cui | Zendy; Fang Li | Zendy; Xiaodan Mao | Zendy; HsunMing Chang | Zendy; Peter C. K. Leung | Zendy; Yinghui Ye | Zendy

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GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability

Author(s) -

Long Cui,

Fang Li,

Xiaodan Mao,

HsunMing Chang,

Peter C. K. Leung,

Yinghui Ye

Publication year - 2018

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-02742

Subject(s) - glial cell line derived neurotrophic factor , oocyte , downregulation and upregulation , biology , neurotrophic factors , microrna , microbiology and biotechnology , endocrinology , gdnf family of ligands , medicine , receptor , andrology , embryo , genetics , gene

Although glial cell line-derived neurotrophic factor (GDNF) and microRNAs (miRNAs) have been shown to regulate mammalian oocyte maturation, little is known about their effects on human oocyte maturation and the underlying molecular mechanisms.

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