Distinctive Desmoplastic 3D Morphology Associated With BRAFV600E in Papillary Thyroid Cancers
Author(s) -
Maxime Tarabichi,
Aline Antoniou,
Soazig Le Pennec,
David Gacquer,
Nicolas De Saint Aubain,
Ligia Craciun,
Thierry Cielen,
Ioanna Laı̈os,
Denis Larsimont,
Guy Andry,
Jacques E. Dumont,
Carine Maenhaut,
Vincent Detours
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-02279
Subject(s) - stromal cell , stroma , desmoplasia , thyroid , thyroid carcinoma , biology , thyroid cancer , exome sequencing , pathology , cancer research , papillary thyroid cancer , phenotype , medicine , immunohistochemistry , gene , endocrinology , biochemistry
Although 60% of papillary thyroid carcinomas are BRAFV600E mutant (PTCV600E), the increased aggressiveness of these cancers is still debated.
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