Altered Expression of miR-181a-5p and miR-23a-3p Is Associated With Obesity and TNFα-Induced Insulin Resistance
Author(s) -
Javier Lozano,
Gemma Llauradó,
Manuel PorteroOtín,
Antonio Altuna-Coy,
Gemma RojoMartínez,
Joan Vendrell,
Rosa Jorba,
Esther RodríguezGallego,
Matilde R. Chacón
Publication year - 2018
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-01909
Subject(s) - insulin resistance , endocrinology , medicine , adipose tissue , proinflammatory cytokine , protein kinase b , pten , insulin , insulin receptor , inflammation , downregulation and upregulation , biology , pi3k/akt/mtor pathway , signal transduction , biochemistry , gene
The proinflammatory cytokine TNFα is a key player in insulin resistance (IR). The role of miRNAs in inflammation associated with IR is poorly understood.
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