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Release and Decay Kinetics of Copeptin vs AVP in Response to Osmotic Alterations in Healthy Volunteers
Author(s) -
Wiebke Fenske,
Ingeborg Schnyder,
Gilbert Koch,
Carla S. Walti,
Marc Pfister,
Peter Kopp,
Martin Faßnacht,
Konrad Strauss,
Mirjam ChristCrain
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-01891
Subject(s) - copeptin , vasopressin , tonicity , medicine , endocrinology , osmole , hypertonic saline , chemistry , arginine , osmotic pressure , biochemistry , amino acid
Copeptin is the C-terminal fragment of the arginine vasopressin (AVP) prohormone whose measurement is more robust than that of AVP. Similar release and clearance characteristics have been suggested promoting copeptin as a surrogate marker.

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