Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer | Zendy

Esther N. Klein Hesselink | Zendy; Carles Zafón | Zendy; Núria Villalmanzo | Zendy; Carmela Iglesias | Zendy; Bettien M. van Hemel | Zendy; Mariëlle S. Klein Hesselink | Zendy; Cristina MonteroConde | Zendy; Raquel Buj | Zendy; Dı́dac Mauricio | Zendy; Miguel A. Peinado | Zendy; Manel PuigDomingo | Zendy; Garcilaso RiescoEizaguirre | Zendy; Jordi L. Reverter | Zendy; Mercedes Robledo | Zendy; Thera P. Links | Zendy; Mireia Jordà | Zendy

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Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer

Author(s) -

Esther N. Klein Hesselink,

Carles Zafón,

Núria Villalmanzo,

Carmela Iglesias,

Bettien M. van Hemel,

Mariëlle S. Klein Hesselink,

Cristina MonteroConde,

Raquel Buj,

Dı́dac Mauricio,

Miguel A. Peinado,

Manel PuigDomingo,

Garcilaso RiescoEizaguirre,

Jordi L. Reverter,

Mercedes Robledo,

Thera P. Links,

Mireia Jordà

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-01613

Subject(s) - thyroid cancer , anaplastic thyroid cancer , medicine , thyroid , cancer , dna methylation , cancer research , oncology , epigenetics , pathology , biology , genetics , gene expression , gene

Global DNA hypomethylation is a major event for the development and progression of cancer, although the significance in thyroid cancer remains unclear. Therefore, we aimed to investigate its role in thyroid cancer progression and its potential as a prognostic marker.

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