Chylomicron-Derived Fatty Acid Spillover in Adipose Tissue: A Signature of Metabolic Health? | Zendy

MarieÈve Piché | Zendy; Siôn Parry | Zendy; Fredrik Karpe | Zendy; Leanne Hodson | Zendy

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Chylomicron-Derived Fatty Acid Spillover in Adipose Tissue: A Signature of Metabolic Health?

Author(s) -

MarieÈve Piché,

Siôn Parry,

Fredrik Karpe,

Leanne Hodson

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-01517

Subject(s) - chylomicron , nefa , endocrinology , medicine , postprandial , adipose tissue , spillover effect , triglyceride , fatty acid , chemistry , cholesterol , insulin , lipoprotein , biochemistry , very low density lipoprotein , economics , microeconomics

Spillover of fatty acids (FAs) into the plasma nonesterified fatty acid (NEFA) pool, because of an inability of adipose tissue (AT) to accommodate sufficient fat uptake, has been suggested to contribute to obesity-related insulin resistance. Using specific labeling techniques, we compared the proportion of spillover-derived NEFA across a range of adiposity.

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