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The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study
Author(s) -
Chino Aneke-Nash,
Xiaonan Xue,
Qibin Qi,
Mary L. Biggs,
Anne Rentoumis Cappola,
Lewis H. Kuller,
Michaël Pollak,
Bruce M. Psaty,
David S. Siscovick,
Kenneth J. Mukamal,
Howard D. Strickler,
Robert C. Kaplan
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-01273
Subject(s) - medicine , diabetes mellitus , hazard ratio , context (archaeology) , proportional hazards model , cohort , population , cohort study , outpatient clinic , confidence interval , risk factor , psychological intervention , gerontology , endocrinology , environmental health , psychiatry , paleontology , biology
Insulin-like growth factor-I (IGF-I) has structural and functional similarities to insulin and may play a role in glucose homeostasis, along with insulin-like growth factor binding protein-3 (IGFBP-3), which binds the majority of circulating IGF-I.

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