Roux-en-Y Gastric Bypass Surgery in the Management of Familial Partial Lipodystrophy Type 1
Author(s) -
Audrey Melvin,
Claire Adams,
Catherine Flanagan,
Lisa Gaff,
Barbara Gratton,
Fiona M. Gribble,
Geoffrey Roberts,
Robert K. Semple,
Stephen O’Rahilly,
Francesco Rubino,
Anna Stears,
David B. Savage
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-01235
Subject(s) - gastric bypass , medicine , lipodystrophy , roux en y anastomosis , gastric bypass surgery , gastric banding , surgery , weight loss , obesity , family medicine , human immunodeficiency virus (hiv) , antiretroviral therapy , viral load
Familial partial lipodystrophy type 1 (FPLD1) is an extreme form of central adiposity, with peripheral lipodystrophy associated with severe manifestations of the metabolic syndrome, often poorly responsive to standard therapeutic approaches. Body mass index in FPLD1 varies but, in many cases, is below the level at which metabolic surgery is usually considered as a therapeutic option.
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