Complement C3 Associates With Incidence of Diabetes, but No Evidence of a Causal Relationship | Zendy

Yan Borné | Zendy; Iram Faqir Muhammad | Zendy; Laura LorésMotta | Zendy; Bo Hedblad | Zendy; Peter M. Nilsson | Zendy; Olle Melander | Zendy; Eiko K. de Jong | Zendy; Anna M. Blom | Zendy; Anneke I. den Hollander | Zendy; Gunnar Engström | Zendy

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Complement C3 Associates With Incidence of Diabetes, but No Evidence of a Causal Relationship

Author(s) -

Yan Borné,

Iram Faqir Muhammad,

Laura LorésMotta,

Bo Hedblad,

Peter M. Nilsson,

Olle Melander,

Eiko K. de Jong,

Anna M. Blom,

Anneke I. den Hollander,

Gunnar Engström

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-00948

Subject(s) - diabetes mellitus , genome wide association study , population , medicine , type 2 diabetes , locus (genetics) , hazard ratio , incidence (geometry) , biology , genetics , endocrinology , confidence interval , genotype , single nucleotide polymorphism , gene , physics , optics , environmental health

This study explored whether complement factor 3 (C3) in plasma is associated with incidence of diabetes in a population-based cohort. We also identified genetic variants related to C3 and explored whether C3 and diabetes share common genetic determinants.

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