Pancreas Fat and β Cell Mass in Humans With and Without Diabetes: An Analysis in the Japanese Population | Zendy

R. Murakami | Zendy; Yoshifumi Saisho | Zendy; Yuusuke Watanabe | Zendy; Jun Inaishi | Zendy; Tami Tsuchiya | Zendy; Kinsei Kou | Zendy; Seiji Sato | Zendy; Minoru Kitago | Zendy; Yuko Kitagawa | Zendy; Taketo Yamada | Zendy; Hiroshi Itoh | Zendy

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Pancreas Fat and β Cell Mass in Humans With and Without Diabetes: An Analysis in the Japanese Population

Author(s) -

R. Murakami,

Yoshifumi Saisho,

Yuusuke Watanabe,

Jun Inaishi,

Tami Tsuchiya,

Kinsei Kou,

Seiji Sato,

Minoru Kitago,

Yuko Kitagawa,

Taketo Yamada,

Hiroshi Itoh

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-00828

Subject(s) - diabetes mellitus , pancreas , glycated hemoglobin , medicine , body mass index , endocrinology , type 2 diabetes , autopsy , population , physiology , gastroenterology , pathology , environmental health

The mechanisms by which β cell mass is reduced in patients with type 2 diabetes remain unclear. It has been postulated that ectopic fat deposits in the pancreas induce β cell apoptosis, leading to the development of diabetes.

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