The Effect of a Subcutaneous Infusion of GLP-1, OXM, and PYY on Energy Intake and Expenditure in Obese Volunteers | Zendy

Tricia Tan | Zendy; Preeshila Behary | Zendy; George Tharakan | Zendy; James Minnion | Zendy; Werd AlNajim | Zendy; Nicolai J. Wewer Albrechtsen | Zendy; Jens J. Holst | Zendy; Stephen R. Bloom | Zendy

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The Effect of a Subcutaneous Infusion of GLP-1, OXM, and PYY on Energy Intake and Expenditure in Obese Volunteers

Author(s) -

Tricia Tan,

Preeshila Behary,

George Tharakan,

James Minnion,

Werd AlNajim,

Nicolai J. Wewer Albrechtsen,

Jens J. Holst,

Stephen R. Bloom

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-00469

Subject(s) - peptide yy , postprandial , medicine , crossover study , appetite , endocrinology , placebo , energy expenditure , anesthesia , insulin , neuropeptide , neuropeptide y receptor , receptor , alternative medicine , pathology

Roux-en-Y gastric bypass (RYGB) surgery is currently the most effective treatment of obesity, although limited by availability and operative risk. The gut hormones Glucagon-like peptide-1 (GLP-1), Peptide YY (PYY), and Oxyntomodulin (OXM) are elevated postprandially after RYGB, which has been postulated to contribute to its metabolic benefits.

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