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Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease
Author(s) -
Layal Chaker,
Tim I.M. Korevaar,
Dimitris Rizopoulos,
TinhHai Collet,
Henry Völzke,
Albert Hofman,
Nicolas Rodondi,
Anne Rentoumis Cappola,
Robin P. Peeters,
Oscar H. Franco
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2017-00410
Subject(s) - percentile , medicine , thyroid function , thyroid disease , thyroid , disease , relative risk , pediatrics , confidence interval , statistics , mathematics
Reference ranges of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) are defined by their distribution in apparently healthy populations (2.5th and 97.5th percentiles), irrespective of disease risk, and are used as cutoffs for defining and clinically managing thyroid dysfunction.

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