Associations of Vitamin D–Binding Globulin and Bioavailable Vitamin D Concentrations With Coronary Heart Disease Events: The Multi-Ethnic Study of Atherosclerosis (MESA) | Zendy

Cassianne RobinsonCohen | Zendy; Leila R. Zelnick | Zendy; Andrew N. Hoofnagle | Zendy; Pamela L. Lutsey | Zendy; Gregory L. Burke | Zendy; Erin D. Michos | Zendy; Steven Shea | Zendy; Russell P. Tracy | Zendy; David S. Siscovick | Zendy; Bruce M. Psaty | Zendy; Bryan Kestenbaum | Zendy; Ian H. de Boer | Zendy

Open Access

Associations of Vitamin D–Binding Globulin and Bioavailable Vitamin D Concentrations With Coronary Heart Disease Events: The Multi-Ethnic Study of Atherosclerosis (MESA)

Author(s) -

Cassianne RobinsonCohen,

Leila R. Zelnick,

Andrew N. Hoofnagle,

Pamela L. Lutsey,

Gregory L. Burke,

Erin D. Michos,

Steven Shea,

Russell P. Tracy,

David S. Siscovick,

Bruce M. Psaty,

Bryan Kestenbaum,

Ian H. de Boer

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-00296

Subject(s) - hazard ratio , vitamin d and neurology , vitamin d binding protein , bioavailability , medicine , confidence interval , cohort , vitamin , coronary heart disease , endocrinology , pharmacology

Low 25-hydroxyvitamin D [25(OH)D] is associated with coronary heart disease (CHD) in people who are white and Chinese but not black or Hispanic. Vitamin D binding globulin (VDBG) avidly binds 25(OH)D, reducing its bioavailability, and differs in isoform and concentration by race.

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