Circulating Klotho Associates With Cardiovascular Morbidity and Mortality During Hemodialysis | Zendy

Christophe Marçais | Zendy; Delphine MaucortBoulch | Zendy; Jocelyne Drai | Zendy; Emmanuelle Dantony | Zendy; Marie-Christine Carlier | Zendy; Emilie Blond | Zendy; Leslie Genet | Zendy; François Kuentz | Zendy; Dominique Lataillade | Zendy; E. Legrand | Zendy; Xavier Moreau-Gaudry | Zendy; Guillaume Jean | Zendy; Denis Fouque | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Circulating Klotho Associates With Cardiovascular Morbidity and Mortality During Hemodialysis

Author(s) -

Christophe Marçais,

Delphine MaucortBoulch,

Jocelyne Drai,

Emmanuelle Dantony,

Marie-Christine Carlier,

Emilie Blond,

Leslie Genet,

François Kuentz,

Dominique Lataillade,

E. Legrand,

Xavier Moreau-Gaudry,

Guillaume Jean,

Denis Fouque

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2017-00104

Subject(s) - klotho , medicine , interquartile range , hemodialysis , dialysis , kidney disease , fibroblast growth factor 23 , diabetes mellitus , cohort , hazard ratio , endocrinology , gastroenterology , kidney , confidence interval , parathyroid hormone , calcium

Klotho gene was identified as an aging suppressor. In animals, klotho overexpression extends life span, and defective klotho results in rapid aging and early death. The kidney is the main contributor to circulating klotho levels, and, during chronic kidney disease, renal klotho gene expression is drastically reduced in animals and humans as well.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research