Insulin Resistance in Youth Without Diabetes Is Not Related to Muscle Mitochondrial Dysfunction
Author(s) -
Melanie CreeGreen,
Ninghe M. Cai,
Laura Pyle,
Brandy M. Ringham,
Mark S. Brown,
Bradley R. Newcomer,
Kristen J. Nadeau,
Dana Dabelea
Publication year - 2017
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2016-3912
Subject(s) - insulin resistance , medicine , endocrinology , type 2 diabetes , triglyceride , context (archaeology) , body mass index , diabetes mellitus , insulin , biology , cholesterol , paleontology
Obesity, insulin resistance (IR), and diabetes are increasing in youth, especially in girls. IR is associated with muscle mitochondrial dysfunction in youth and adults with diabetes. However, it is unknown whether this relationship is present in youth prior to development of diabetes.
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