Effect of Combined Hormonal Replacement Therapy on the Aldosterone/Renin Ratio in Postmenopausal Women | Zendy

Ashraf Ahmed | Zendy; Richard D. Gordon | Zendy; Gregory J. Ward | Zendy; Martin Wolley | Zendy; Brett McWhinney | Zendy; Jacobus Ungerer | Zendy; Michael Stowasser | Zendy

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Effect of Combined Hormonal Replacement Therapy on the Aldosterone/Renin Ratio in Postmenopausal Women

Author(s) -

Ashraf Ahmed,

Richard D. Gordon,

Gregory J. Ward,

Martin Wolley,

Brett McWhinney,

Jacobus Ungerer,

Michael Stowasser

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-3851

Subject(s) - medicine , endocrinology , aldosterone , plasma renin activity , medroxyprogesterone , medroxyprogesterone acetate , creatinine , renin–angiotensin system , primary aldosteronism , hormone , blood pressure

Plasma aldosterone/renin ratio (ARR) is the most popular screening test for primary aldosteronism (PA). Because both estrogen and progesterone (including in oral contraceptive agents) affect aldosterone and renin levels, we studied the effects of combined hormonal replacement therapy (HRT) on ARR; renin was measured as both direct renin concentration (DRC) and plasma renin activity (PRA).

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