Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade | Zendy

Morten Høgild Pedersen | Zendy; Mads Svart | Zendy; Janne Lebeck | Zendy; Martin Bidlingmaier | Zendy; Hans StødkildeJørgensen | Zendy; Steen B. Pedersen | Zendy; Niels Møller | Zendy; Niels Jessen | Zendy; Jens Otto Lunde Jørgensen | Zendy

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Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade

Author(s) -

Morten Høgild Pedersen,

Mads Svart,

Janne Lebeck,

Martin Bidlingmaier,

Hans StødkildeJørgensen,

Steen B. Pedersen,

Niels Møller,

Niels Jessen,

Jens Otto Lunde Jørgensen

Publication year - 2017

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2016-3835

Subject(s) - medicine , endocrinology , insulin resistance , glucose clamp technique , lipolysis , insulin , intermittent fasting , carbohydrate metabolism , basal (medicine) , adipose tissue , pancreatic hormone

Insulin resistance and metabolic inflexibility are features of obesity and are amplified by fasting. Growth hormone (GH) secretion increases during fasting and GH causes insulin resistance.

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