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Increased microparticle (MP) shedding by placental trophoblasts contributes to maternal vascular inflammatory response and endothelial dysfunction in preeclampsia. Vitamin D has beneficial effects in pregnancy; however, its effect on trophoblast MP release has not been investigated.

Vitamin D Reduces Oxidative Stress–Induced Procaspase-3/ROCK1 Activation and MP Release by Placental Trophoblasts